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 MeReC

Supplement 3

Examples of sources of information that may be informative in the absence of NICE guidance and Dealing with sources of information
To accompany
MeReC Bulletin Vol 16 No 2: National Institute for Health and Clinical Excellence. March 2006.

Examples of sources of information that may be informative in the absence of NICE guidance
      Disease Management
      Individual treatments/technologies
Dealing with sources of information

Examples of sources of information that may be informative in the absence of NICE guidance

Disease management

PRODIGY guidelines - advice on management of conditions and symptoms commonly seen in primary care.

Clinical Evidence - summaries of the current state of knowledge and uncertainty about the prevention and treatment of clinical conditions, based on thorough searches and appraisal of the literature.

Cochrane Library - a regularly updated collection of evidence-based medicine resources, including The Cochrane Database of Systematic Reviews. This contains the full text of evidence based systematic reviews of health care interventions, prepared by The Cochrane Collaboration.

NHS Cost and Effectiveness Reviews - produced by the Centre for Reviews and Dissemination at the University of York. Includes DARE (Database of Abstracts of Reviews of Effectiveness - a database of quality-assessed reviews of the effects of treatment) and NHSEED (NHS Economic Evaluation Database - comparisons of two or more treatment or care alternatives by cost-benefit analysis, cost-utility analysis, or cost-effectiveness analysis).

Drug and Therapeutics Bulletin - provides rigorous and independent evaluations of individual treatments and overall management of disease for healthcare professionals. Also produces similar information for patients in the form of Treatment Notes. Only available outside NHSnet with an Athens password (available to employees who work for, deliver services on behalf of, or work in conjunction with the NHS).

NHS Health Technology Assessment (HTA) programme - commissions high quality research on the costs, effectiveness and broader impact of health technologies in the NHS.

Guidelines Finder - A searchable database of UK clinical guidelines.

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Individual treatments/technologies

  • National Prescribing Centre (NPC) and UK Medicines Information (UKMI) bulletins - designed to inform key purchasers in primary and secondary care of new drugs which may have significant therapeutic, financial and service impact on the health service. Evaluations are prepared either several months before launch or within a few months of launch. The London New Drugs Group is a part of UKMI that particularly focuses on new medicines. (NB Some of the information on these websites is password protected for a restricted audience.)
  • National Horizon Scanning Centre technology briefings - provide advance notice of significant new and emerging health technologies to the Department of Health.
  • NHS Cost and Effectiveness Reviews, Drug and Therapeutics Bulletin, NHS HTA programme (explained above). See www.nelh.nhs.uk
  • Scottish Medicines Consortium - provides advice to NHS Boards and their Area Drug and Therapeutics Committees across Scotland about the status of all newly licensed medicines, all new formulations of existing medicines and any major new indications for established products.
  • Midlands Therapeutic Review and Advisory Committee (MTRAC) - an independent committee of GPs and representatives of other key decision-makers in the use of medicines in primary care. They provide assessments of selected medicines on their clinical value, safety and suitability for use in primary care in the West Midlands Region. The recommendations of the Committee and the evidence considered in the evaluations are summarised in verdict and summary sheets.
  • Northern and Yorkshire Regional Drug and Therapeutics Centre (NYRDTC) - aims to promote safe, effective and economical use of medicines in the NHS in the Northern and Yorkshire Region. The centre delivers a broad range of services relating to prescribing and the use of medicines. These include critical appraisal and drug evaluations.

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Dealing with sources of information

Information Mastery: Feeling good about not knowing everything

Information Mastery consisted of two conferences hosted by the National Prescribing Centre in March 2005, run by the founders of InfoPOEMs (information on patient-oriented evidence that matters), Profs David Slawson and Allen Shaughnessy. Information Mastery was designed to help healthcare practitioners to develop effective ways of identifying, filtering, evaluating, using and, most importantly, applying new information to enhance patient care.

The conference and supporting materials explain how to assess the usefulness of information by determining its relevance and validity. Usefulness is also dependant on how much time and effort it takes to search for the information required. Therefore, rather than trying to stay up to date by reading, the course shows busy healthcare professionals how to search quickly to find the best answer to clinical problems they face.

The evaluation of information can be expressed as a formula:

Usefulness =       relevance x validity
                          time and effort required

The following supporting materials to this conference are available:

Using evidence to guide practice: MeReC Briefing No. 30. September 2005

This Briefing discusses approaches for sourcing the most useful evidence about interventions and explains some of the concepts necessary for its interpretation to help healthcare professionals and patients decide which interventions are appropriate for their care. It is supported by an online supplement.

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